Modified inspiratory flow pattern - a tool for lung protective ventilation
نویسندگان
چکیده
Introduction Lung protective ventilation, LPV, is recommended for ever wider patient populations, even those without primary lung disease. Low tidal volume ventilation is a first-hand remedy for LPV that is facilitated by dead space reduction. Inspiratory flow pattern affects gas exchange. In ARDS patients, it was recently shown that a long period during which inspired tidal gas is in contact with resident alveolar gas, mean distribution time, MDT, as well as a high end inspiratory flow, EIF, immediately before interruption of inspiration augment exchange of C02 by reduction of airway and alveolar dead space.
منابع مشابه
An appropriate inspiratory flow pattern can enhance CO2 exchange, facilitating protective ventilation of healthy lungs.
BACKGROUND In acute lung injury, CO2 exchange is enhanced by prolonging the volume-weighted mean time for fresh gas to mix with resident alveolar gas, denoted mean distribution time (MDT), and by increasing the flow rate immediately before inspiratory flow interruption, end-inspiratory flow (EIF). The objective was to study these effects in human subjects without lung disease and to analyse the...
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